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So, if you're feeling unwell due to a deficiency, restoring B12 levels might help you feel well enough to eat normally, but it's not "making" you gain weight in an unhealthy way

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For fate mapping experiments, often short time windows for reporter gene activation are preferred

Oral supplements have also been shown to be effective at treating vitamin B12 deficiency

What the evidence does not establish: Human efficacy at clinically meaningful magnitudes, long-term safety, cardiovascular profile under chronic dosing