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Various modulators, such as LONP1 [56], SMAD4 [57], Thiostrepton (TST) [58], verteporfin [59], and tomatidine [60], regulate GPX4 expression at the transcriptional level to induce ferroptosis in PDAC cells

Factors such as specific citrus varieties, cultivation methods, ripeness at the time of juice extraction, and processing techniques can influence the final hesperidin concentration in the juice

The nervous system is vulnerable to oxidative stress because of high oxygen metabolism in the brain (Zhao et al., 2012)

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Oxidative stress in subarachnoid haemorrhage: significance in acute brain injury and vasospasm

Meyer ML, Peters S, Janne PA, Mok TS, Bunn PA, Abdel Karim N, Altorki NK, Arrieta O, Bar J, Cappuzzo F, Carbone D, Dacic S, Diehn M, Dziadziuszko R, Felip E, Flores R, Florez N, Forde PM, Gainor JF, Gray JE, Gros L, Halmos B, Henschke CI, Herbst R, Heymach JV , Kelly K, Kris MG, Leighl NB, Mathias C, Marron TU, Mulshine JL, Naidoo J, Osarogiagbon R, Passaro A, Peled N, Planchard D, Politi K, Popat S, Pyenson B, Reckamp KL, Ren SH, Riely GJ, Rolfo C, Rudin CM, Sen T, Shields MD, Singh H, Skoulidis F, Solomon BJ, Stahel R, Stiles BM, Syrigos K, Yang JC, Yang PC, Wolf A, Wozniak AJ, Waqar SN, Wakelee H, Hirsch FR