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Furthermore, pristine SiO 2 NPs, which could not be taken up by erythrocytes, were shown to promote ROS-mediated and caspase-3-dependent eryptosis [452] (Fig

The first step is to modify the chemotherapy regimen, such as dose reduction and longer interval between cycles, especially platinum agents like oxaliplatin or cisplatin and vincristine [63]

*Correspondence: Wenjun Wang, [email protected] This article was submitted to Aquatic Physiology, a section of the journal Frontiers in Marine Science Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

However, challenges include heterogeneity of redox responses, selective targeting of ROS in cancer cells, and combination therapy [82]

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Because of these reactions, they produce the hydroxyl anion (OH ) and OH