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Upon proteolytic degradation, these residues undergo a series of enzymatic reactionsincluding hydroxylation, aldol cleavage, and aldehyde oxidationleading to the formation of 4-trimethylaminobutyric acid (-butyrobetaine), which is subsequently converted into l-carnitine through the catalytic action of -butyrobetaine dioxygenase (BBOX1) 25,26

[DOI] [PMC free article] [PubMed] [Google Scholar] 191.Le Bastard Q., Al-Ghalith G.A., Grgoire M., Chapelet G., Javaudin F., Dailly E., Batard E., Knights D., Montassier E

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Abstract Background Carnitine plays a crucial role in the metabolism of fatty acids as well as energy production

5 The actual incidence of liver injury by statins is considered to be much lower than general aminotransferase abnormalities, around 1%

Kadoch, C