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Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation

Immune System Enhancement : Alcohol consumption can weaken the immune system

SOME PEOPLE MAY BENEFIT HAVING THEIR FIRST 4 SHOTS CLOSER TOGETHER TO GET A GOOD BOOST AND THEN MAINTAIN WITH MONTHLY SHOTS AFTER

You need to increase the levels of vitamin B12 in your body in order to alleviate symptoms and prevent deficiency from reoccurring

After an initial loading regimen of 1mg three times weekly for two weeks, maintenance therapy is typically 1mg every three months for life in conditions like pernicious anaemia, or every two months if neurological involvement was present

Nutrition & Exercise Foundation The backbone of weight loss remains diet, movement, and behavioral support