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This non-essential amino acid can be transformed into glutamate and then into -ketoglutarate (KG), which like glucose-derived acetyl-CoA, is an essential fuel for the TCA cycle [ Fatty acids Fatty acids (FAs) can fuel cellular metabolism through FA oxidation (FAO), another source of acetyl-CoA, which can then be shuttled to the TCA cycle

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Thirty patients received traditional hydration therapy, consisting of saline, mannitol (Osmitrol), and the diuretic furosemide (Lasix), and 20 patients received modified hydration therapy, consisting of saline, mannitol, and magnesium, but not furosemide