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Table 1 Adrenal hormonal imbalance-associated oxidative stress

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This finding has led to modifications in behavioral activation therapy protocols to emphasize effortful activities that generate natural dopamine responses

Recent studies suggest that a cytoprotective mechanism regulates BAX translocation to mitochondria through BAXHumanin (Guo et al , 2003) and BAXapoptosisassociated specklike protein (Ohtsuka et al , 2004)