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146 Osteosarcoma cell lines and tissues show low expression of miR-144-3p and high expression of its target gene ZIB1, and miR-144-3p level is negatively correlated with the invasion and migration ability of osteosarcoma cells

These findings highlight the need for standardized protocols to assess the complexity of ibuprofen and microplastics effects on reproduction accurately ( Ibuprofen exposure decreased the total egg count

compounds such as phytates commonly present in legumes can inhibit the absorption of minerals like iron and zinc, indirectly affecting overall polyphenol bioavailability, while co-ingestion of proteins and fats alters digestive processes and thereby influences polyphenol absorption (Craig & Roberts, 2025)

Increased expression of VDR and -1-hydroxylase can occur in response to activation of pattern recognition receptors such as Toll-like receptors and NOD-type receptors

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Preclinical research has shown that L-methionine supplementation can directly activate the hepatic SIRT1/AMPK signaling pathways, which are crucial for regulating cellular energy homeostasis and improving circulating lipid profiles