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Description

McDonald, J

This rapidly-growing area of basic and translational research was initiated in 2013 by the demonstration of increased CBS expression and H 2 S generation in surgically excised tissues of colon cancer patients (compared to non-cancerous surrounding tissues), and the demonstration of the functional tumor-supportive bioenergetic and pro-angiogenic roles of CBS-derived H 2 S in various cell-based and animal models of colon cancer [6]