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Intson et al., 2022)

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What Cycling Means (And Why People Assume It Is Necessary) Cycling typically implies: Using a compound for a fixed period Stopping to reset receptors Restarting later to regain effectiveness This idea comes primarily from: Anabolic steroid use Stimulant tolerance Certain GPCR-activating peptides Central nervous system drugs AOD-9604 fits none of those categories

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This involved treating both control and NINJ1 knockdown cells with DMSO or erastin, either alone or in combination with various compounds

doi: 10.1513/AnnalsATS.201503-133AW 140 FratiFSalvatoriCIncorvaiaCBellucciADi CaraGMarcucciFet al