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BisAbs contain engineered disulfide bonds for structural stability, which have been previously implicated in BisAb aggregation 3

59 In renovascular hypertension, oxidative stress in the ischemic kidney has a major role in the maintenance of hypertension in two kidney-one clip rats

Liver IRI is characterized by two interlinked phases: ischemia-induced hepatocyte injury, leading to the release of damage-associated molecular patterns, and subsequent recruitment of immune cells, initiating an inflammatory cascade that exacerbates hepatocyte damage

F112 is shown in the conformations in crystal structures obtained without (blue) and with (magenta) (-)-catechin ( 12 ) and its surface is rendered transparently