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At the molecular level, fatigue affects calcium handling within muscle fibers, disrupting excitation-contraction coupling and reducing force production

It plays a crucial role in: Neutralizing free radicals Supporting liver detoxification Protecting skin cells from oxidative stress Maintaining overall cellular health Over time, factors like pollution, stress, aging, UV exposure, and poor sleep reduce glutathione levels

These changes tend to be associated with normal signs of aging like poor wound healing, thinning of the skin, and no tissue regeneration

Given the well-established risk of B12 deficiency after sleeve gastrectomy, lifelong supplementation is widely recommended by bariatric surgery teams across the UK

At these therapeutic concentrations, glutathione actively inhibits tyrosinase the enzyme responsible for melanin production resulting in progressive skin brightening, tone unification, and a visible reduction in pigmentation