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It is being co-developed by Boehringer Ingelheim and Zealand Pharma, and as of 2026 it has moved through a substantial Phase 2 package into a large Phase 3 program while remaining unapproved by any regulator

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These core mechanisms include the synthesis of short-chain fatty acids (SCFAs) and vitamins, the promotion of immune system maturation, and the competitive exclusion of pathogenic microorganisms [35, 36]

doi: 10.1038/s41556-020-0496-x 111 DodsonMCastro-PortuguezRZhangDD

10.1016/j.neuroscience.2016.06.050 69 DurandJ