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Supplementation of Direct Antioxidants There are various antioxidants with the ability to directly eliminate ROS, such as vitamins, carotenoids, polyphenols, and lipoic acid, which are widely present in food and are often taken as dietary supplements [118, 119, 120, 121]

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In this context, however, the thiol antioxidant glutathione (GSH) represents a dominant defence system with the capacity to neutralize a broad range of both ROS and RNS [39]

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This nanoplatform demonstrated effective suppression of circADARB1 expression with concurrent iron accumulation, and synergistic enhancement of radiotherapy efficacy through promoted ferroptosis and increased radiosensitivity in NPC cells (Wang D

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