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Of note, it was counteraction of the leg contracture, which was assessed immediately after the intramuscular injection of succinylcholine, after the cessation of overt symptoms of muscle involvement, and then at the subsequent following days

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The direction of treatment changed following the adverse outcomes highlighted by the Cardiac Arrhythmia Suppression Trial (CAST) and the Survival with Oral D-Sotalol (SWORD) trial, which demonstrated that patients receiving AADs (encainide or flecainide) fared worse than those on placebo (6)

"The advice that I had at that time was that AOD-9604 was considered under section S2 of the anti-doping code and was regarded as not prohibited

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