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Eine bermige und anhaltende Stimulation der somatotropen Achse knnte theoretisch Effekte hnlich der Akromegalie hervorrufen: Wasserretention, Arthralgien, Karpaltunnelsyndrom, Insulinresistenz und potenziell ein erhhtes Proliferationsrisiko bestimmter IGF-1-empfindlicher Tumorzellen

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