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L-carnitine is able to be synthesized in the hepatic and renal systems of humans and dogs, this is not possible within the cardiac or skeletal muscle and thus L-carnitine is either absorbed from the diet or biosynthesized by other tissues (Verney et al

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Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M (1997) Alpha-synuclein in Lewy bodies

Consistent with these effects, the mRNA expression of genes involved in -oxidation was compensatorily up-regulated in the d-carnitine group