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Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine

PMID: 23818692

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This review comprehensively discusses the sources and mechanisms of ROS generation, the associated pathophysiology of diseases, and the role of both endogenous and exogenous antioxidants in mitigating oxidative stress

However, low and medium doses led to the upregulation of Treg-associated genes and an increase in Foxp3 + cells in gut tissues, suggesting that low-dose immunotherapy promotes local regulatory T cell induction and regulatory cytokine upregulation