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PMID 30121905

However, both drugs can cause stomach discomfort, diarrhea, and constipation, especially during dose escalation

Additionally, conventional antidepressants display remarkable limitations, such as the delayed onset of action, low response rates, and relapse following medication discontinuation, impeding treatment compliance in patients with depression (Sabella, 2018)

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Before and after photos, DEXA scans , and IGF-1 labs are often used to track progress during the 6090 day treatment window

Here, for the first time, our work clarified the detailed mechanism on how TRPM7 participates in pyroptosis and epileptogenesis, and how targeting TRPM7 may pave the way for a new generation of drugs to treat SE and other neurological conditions, among which neuronal pyroptosis is a hallmark pathology