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It is very difficult to observe the DHA-bound OsDHAR complex structure because DHA is very unstable and easily degraded in solution

used C57BL/6 mice as the animal model to induce oxidative stress using paraquat (McCormack et al., 2005)

caloric restriction, low glucose availability, exercise, and ischemia, cells can promote sirtuins activation by increasing NAD + -production as previously described

Results Paraquat-Induced Inhibition of GSNOR Activity S -nitrosoglutathione-reductase controls intracellular levels of SNOs and thereby this enzyme is important for NO homeostasis

Library construction and sequencing were performed by the Illumina PE150 platform at HaploX Biotechnology (Shenzhen, China)