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A disulfide bond is a covalent chemical bond between two sulfur atoms that can arise from the oxidative linking of two sulfhydryl (thiol) groups

A significant increase in BDNF was observed (p=0.26) representing a strong correlation with melatonin concentrations, indicating that BDNF is a key regulator for circadian rhythm sleep-wake disorders (14)

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Also polymorphisms of EAAT1 and EAAT2 were proposed to be associated with cognitive performance in schizophrenia [111]