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Overall, the preclinical package detailed above will support the initiation of a Phase 1/2 study, with first patient dosed planned for Q4 2024

Beyond the contamination risk, the lack of preservative means the solution degrades faster

Adequate magnesium and other essential minerals matter too, on a simple competition logic: when the good minerals are present, metals have fewer open binding sites to occupy

[18] Time elapsed since initial diagnosis of diabetes and duration and dose of metformin use were recorded following a review of medical records

Vitamin B12 Health Professional Fact Sheet

Still, because NAD+ injections are a relatively novel therapy, patients should be monitored for any unexpected reactions