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This involves inactivation of anti-apoptotic Bcl-2 proteins, including Bcl-2, Bcl-xL and Mcl-1L and the translocation and oligomerization of pro-apoptotic proteins, such as Bax and Bid, within the mitochondrial membrane

Study of the association between glutathione S-transferase (GSTM1, GSTT1, GSTP1) polymorphisms with type II diabetes mellitus in southern of Iran

doi: 10.3390/antiox11122308

ACS Cent Sci 6, 4153

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The guidelines state, However, pernicious anaemia in its true sense (that is, life-threatening anaemia) is now extremely rare because of developments in testing and treatment for, and greater awareness of, vitamin B 12 deficiency . In one sense, this statement is correct: the term pernicious anaemia, when taken literally, implies a severe, life-threatening form of anaemia, which is uncommon in modern practice due to improvements in testing and treatment, such severe manifestations are typically prevented, as the condition is more likely to be diagnosed earlier or treated with B 12