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Senescence and p53 Demaria et al

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8 Reduction or deletion of GGT1 expression does not impair GSH-mediated rescue of cells in cystine-free conditions

The second group includes peptides mimicking the effects of botulinum neurotoxins whereas the third group, the carrier peptides, acts by delivering trace elements required for enzymatic processes

This is why ex vivo findings need to be confirmed in human trials which subsequent studies like the 2016 GHK peptide clinical trial and the 2021 copper tripeptide serum trial have done