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This is the first study to show that GPX3 is regulated by TGF- in a cell-type-specific manner

Estrogens signal through myriad pathways, including genomic mechanisms mediated by two nuclear receptors (ER and ER) that recruit various co-regulatory proteins and induce transcription at estrogen response elements (EREs), in addition to other promoters by tethering to transcription factors (e.g., AP-1 and NF-B)

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Moreover, there was an association between cfDNA levels and disease activity (44, 45)