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Description

Biomacromolecules 15 , 44804487 (2014)

In addition to optical isomers, astaxanthin displays geometric (E/Z) isomerism due to multiple conjugated double bonds in its polyene chain, with all-trans (all-E) being the major configuration in nature and 9-cis, 13-cis, and 15-cis isomers reported under certain conditions such as heat or light exposure

Additionally, the endogenous administration of BDNF was shown to protect neurons within the substantia nigra from 6-OHDA and MPTP toxicity, both in rat and primate Parkinson models [31]