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Nevertheless, DKP is a known metabolite of AX that can arise as well by thiol-independent mechanisms, including the acidic degradation of AX ( Figure 2 Figure 3 Next, the incubation experiments were carried out in PBS buffer at 37C using different AX : DTT ratios ( Table 1 ), and the progress of the reaction was monitored by 1 H-NMR using the chemical shifts for AX -lactam ring protons (H5 and H6)

Yu D, Marchiando AM, Weber CR, Raleigh DR, Wang Y, Shen L, Turner JR

positive or negative

The value of each biological replicate was normalized

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The severity of a B12 deficiency plays a key role, as does the type and severity of nerve pain