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Mol Biochem Parasitol 148(2):219222

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An accumulation of lactate to dangerous levels ( lactic acidosis ) can occur when metformin is taken by patients with other conditions resulting metabolic acidosis (liver disease, heart failure, sepsis, alcohol abuse), or kidney disease (as indicated by elevated creatinine levels) because metformin is eliminated by renal excretion) (He & Wondisford, 2015

Centro De Investigacin Biomdico En Red Enfermedades Hepticas y Digestivas (CIBERehd), Madrid, Spain, (2)University Hospital Virgen De La Victoria, Ibima Plataforma Bionand, Universidad De Mlaga, Mlaga, Spain

He presented Early Infantile Developmental and Epileptic Encephalopathy (EI-DEE) in the absence of other specific systemic involvement and unrevealing first-line biochemical findings

Other Names for This Condition Abdominal migraine CVS Cyclical vomiting Cyclical vomiting syndrome Periodic vomiting Additional Information & Resources Patient Support and Advocacy Resources Clinical Trials Catalog of Genes and Diseases from OMIM Scientific Articles on PubMed References Abell TL, Adams KA, Boles RG, Bousvaros A, Chong SK, Fleisher DR, Hasler WL, Hyman PE, Issenman RM, Li BU, Linder SL, Mayer EA, McCallum RW, Olden K, Parkman HP, Rudolph CD, Tache Y, Tarbell S, Vakil N