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Aim: To study the outcome of high-risk hyperimmunized patients (D/R positive crossmatch or high MFI titers of pDSA at time of transplant) transplanted and receiving induction therapy using rATG and IVIG after LT

504,505,506 GLP-1 enhances the insulin signaling pathway in the liver by activating the GLP-1R, especially through the phosphorylation of insulin receptor substrates and the activation of the PI3K/Akt signaling pathway, thereby increasing hepatic insulin sensitivity, facilitating glucose uptake and utilization, and reducing hepatic gluconeogenesis