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Here, we report two cryo-EM structures of Ycf1 at 3.4 and 4.0 resolution in inward-facing open conformations that capture previously unobserved ordered states of the intrinsically disordered regulatory domain (R-domain)

Chronic dietary choline represses age-related loss of dentritic spines in mouse neocortical pyramidal cells

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Frequent dosage adjustments for some immunosuppressive drugs that require therapeutic drug monitoring and dose titration based on blood concentrations, such as tacrolimus, tend to occur more often in newly transplanted recipients, and less frequently once patients are on stable regimens

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3 Therapeutic potential of GA for the pathogenetic basis of ASCVD Hyperlipidemia, arterial stiffening, and AS collectively constitute the core pathological basis of ASCVD (Dutta et al., 2024