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These DFT calculations provide mechanistic insights into the enzymatic activities of CuSAE, supporting the experimental observations of the NADPH oxidase activity and confirming the catalytic properties of the nanozyme

A novel combination therapy using Rosuvastatin and lactobacillus combats dextran sodium sulfate-induced colitis in high-fat diet-fed rats by targeting the TXNIP/NLRP3 interaction and influencing gut microbiome composition

Altogether, these examples underscore that despite encouraging experimental results, ferroptosis-targeted drugs face multiple translational bottlenecks, including systemic toxicity, insufficient targeting, metabolic compensation, and biological heterogeneity

Myeloperoxidase - a bridge linking inflammation and oxidative stress with cardiovascular disease

Jonathan C

Aveli precisely identifies and releases those bands in real time