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The resulting precipitate was isolated by filtration, washed once with fresh acetone and dried under reduced pressure to give 737 mg of the compound of formula 31 as a yellow powder

A recent report from the Vander Heiden group specifically addressed this issue by testing whether tissue-of-origin dictates cancer dependence on specific metabolic pathways (134)

However, much more work is needed to apply this strategy in the clinic

& Sagi, S

doi: 10.1007/s00401-010-0763-1 45 RamkissoonLAHorowitzPMCraigJMRamkissoonSHRichBESchumacherSEet al

KI95: 4.5-79.1, p 4 in the past 7 days, antihistamines were used by 19 (40%), bile acid binding resins by 12 (25%), rifampin by 7 (15%), sertraline by 4 (9%), and fenofibrate by 4 (8%)