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In humans, vitamin B 3 (also known as niacin, the generic name for nicotinic acid and nicotinamide) is the primary substrate for NAD + and NADP + synthesis, and TRP is the alternative substrate [97]

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Proctor EC, Turton N, Boan EJ, Bennett E, Philips S, Heaton RA, Hargreaves IP (2020) The effect of methylmalonic acid treatment on human neuronal cell coenzyme q10 status and mitochondrial function

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System suitability requirement: The resolution between each chromatographic peak in the chromatogram of the reference solution should meet the requirements