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10.1007/s12975-014-0340-3 12 GaoX.ZhangY.BurwinkelB.XuanY.HolleczekB.BrennerH.et al (2019)

One practical note worth knowing before you order: this product is heat sensitive

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CB-1158 could block myeloid cell-mediated inhibition of T cell proliferation, increase the number of tumor-infiltrating CD8 + T cells and NK cells, and increase the expression of inflammatory factors and interferon-, thereby changing the immune microenvironment to promote inflammation and reduce tumor immune escape, inhibiting tumor cell proliferation

General storage considerations include: Maintaining stable temperature conditions Protecting the material from unnecessary light exposure Avoiding moisture exposure Keeping containers tightly closed Minimizing repeated freeze-thaw cycles when applicable Labeling all materials clearly Restricting access to trained personnel Recording storage dates and conditions Storage logs should include the product name, batch number, storage location, date received, date opened, and any observed changes in material appearance

These backup mechanisms facilitate the survival and proliferation of cancer cells [26,48,52]