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Caudatin has also displayed neuroprotection in models of Alzheimers disease by activating TFEB and the autophagosome-lysosomal pathway mechanism of action, while also modulating PPAR

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A longitudinal study conducted involving 1,347 community-dwelling older Australian women over 14.5 years reported a dose-dependent positive relationship between vitamin K1 intake and physical function, as well as a lowered risk of long-term injurious falls with higher intake ( A randomized controlled trial with 30 participants aged 4074 years conducted over three 4-week experimental phases found that the consumption of green leafy vegetables rich in vitamin K1 significantly reduced serum levels of total and uncarboxylated osteocalcin, showing potential for bone material property improvement ( The relationship between vitamin K supplementation and BMD is less conclusive

26 This may be due in part to age-related changes in cochlear structures and nerve function and connectivity

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