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These data suggest susceptibility to further oxidation to sulfonic acid, which would appear as a loss of signal

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G6PDH deficiency G6PDH deficiency is one of the most common enzyme defects in humans due to multiple mutations of the G6PDH gene and imparts different phenotypes, from acute hemolytic anemia to chronic hemolysis (30)

FIGURE 2 5.2 Clinical application of intranasally delivered drugs Although IN delivery of iron chelators remains in the early preclinical stages and has not yet entered clinical trials, the broader field of IN route has gained increasing attention over the past decade, as evidenced by a notable rise in related clinical studies

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