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PDZ1 binds the C-terminus of claudins (106) while the GUK domain interacts with occludin (107)

Glutamate concentrations in neurons are highest at axon terminals, which means that axon terminals somehow restrict glutamate movement or local synthesis and utilization of glutamate, and glutaminase is responsible for glutamate synthesis in most neurons (Mrquez et al., 2009

In short, human tissues, blood, and urine contain a mixture of arsenic metabolites that vary in acute and chronic toxicity

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These inhibitors have been shown to exhibit highly efficient antiproliferative properties in pancreatic cancer [162]

How TCM interferes with autophagy to improve DCM is a promising research direction and may also be one of the focuses of future research work