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Genome stability, progressive kidney failure and aging

Funding: Supported by NIH grants P30 DK056341 (Washington University Nutrition and Obesity Research Center), P30 DK020579 (Washington University Diabetes Research Center), UL1 TR000448 (Washington University Institute of Clinical and Translational Sciences), and T32 DK007120, and the Barnes-Jewish Hospital Foundation

This consistency is crucial for researchers to meet experimental timelines and have continuous access to research materials

Because topical rapamycin can make skin more sensitive to sunlight, apply SPF 30+ daily and avoid excessive sun exposure

These data are consistent with the T allele decreasing risk for T2D, as well as decreasing glucose and HbA1c levels, but slightly increasing the risk of smoking initiation (Supplementary Table 16)