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Description

Does AOD-9604 support joint health

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With MTRR/MTR inhibition, the compensation pathway is BHMT (betaine-homocysteine methyltransferase (betaine to dimethylglycine)

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Pharmacokinetic studies in rats demonstrated an oral bioavailability of 38.4%, with a mean Cmax of 2,252 ng/mL and terminal elimination half-lives of 3.80 1.10 hours (IV) and 6.90 1.20 hours (oral) (Awosemo et al., 2021)