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The study comparing a diet with high fat/high sucrose and high fat/high sucrose with cranberry extract revealed that polyphenols lowers total weight gain, visceral adipose tissue weight, hepatic triglyceride accumulation, and plasma cholesterol levels ( in vitro study has also demonstrated that the polyphenols contained in pomegranate extracts in combination with probiotics induces synergistic effects that substantially reduces the triglyceride levels and intracellular lipid increase (Sorrenti et al., 2019)

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Vitamin C plays an important role to keep glutathione in its reduced form so that it can continue to provide free radical-quenching effects [2-5]

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Patients also receive a medication called mesna (Mesnex) to avoid cystitis, a severe irritation of the bladder that can occur with cyclophosphamide therapy