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Comp Biochem Physiol C Toxicol Pharmacol 206:110

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However, the more pronounced differences in astrocyte reactivity, microglial activation, oxidative stress, tissue swelling and demyelination within the cuprizone pellet group compared to their controls at 3 weeks, despite no significant weight loss, suggest that weight loss may not be a reliable proxy of the extent of demyelinating disease

Origins of ultrasensitivity and complex signaling dynamics of cellular hydrogen peroxide and peroxiredoxin

Unconjugated hyperbilirubinemia results from overproduction, decreased hepatic uptake, or impaired conjugation of bilirubin