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Serious adverse effects are uncommon in healthy adults but can include elevated homocysteine levels if methionine metabolism is impaired, which is why patients with MTHFR gene variants should use methylated B-vitamin formulations instead of standard Lipo C

doi: 10.1016/j.redox.2023.102659 37 LiuSJiaYMengSLuoYYangQPanZ

B12 is an essential nutrient, and its deficiency is common, especially among individuals following restricted diets like vegetarianism or veganism, pregnant or breastfeeding women, older adults, those who have undergone gastrointestinal surgery or have gastrointestinal disorders, and people with an autoimmune condition known as pernicious anaemia

Doering TL

Wang Y, Branicky R, Noe A et al (2018) Superoxide dismutases: dual roles in controlling ROS damage and regulating ROS signaling

Dehydration during pregnancy can lead to serious complications, including: Low amniotic fluid levels (oligohydramnios) Neural tube defects Premature labor Poor breast milk production after delivery Nutrient Deficiencies When severe morning sickness prevents adequate nutrition, IV therapy can deliver essential nutrients directly to your bloodstream