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Description

One drink early in the day is far less damaging than 2 to 3 drinks close to bedtime: timing matters more than total volume

Contraindications include active or recent cancer, uncontrolled diabetes, severe diabetic retinopathy, and pregnancy

10.1016/S0140-6736(19)32008-2 163 ZaccariaM.VarnierM.PiazzaP.NoventaD.ErmolaoA

Targeting FGFR for cancer therapy

IGF-1 DES: Comparing the Two Major Truncated Analogues IGF-1 DES (des(1-3)-IGF-1) lacks the first three N-terminal amino acids of native IGF-1

A 2020 review in Diabetes Care noted that "the hypoglycaemic effect of IGF-1 has been exploited therapeutically in rare forms of insulin-receptor-defect syndromes, but the risk-benefit calculation differs fundamentally from use in euglycaemic individuals" [20]