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(2024), involving both primiparous and multiparous cows managed under different late-gestation feeding regimes (non-supplemented, dried distillers grains [DDG]-based diets, and RPM supplementation), showed limited effects on the performance of both dams and progeny

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Cystine/glutamate antiporter (System Xc-), acting as a System Xc- on the cell membrane, regulates the upstream pathways of ferroptosis by primarily transporting extracellular cystine into the cell for GSH synthesis

10.1137/1.9780898718195 11 Fisher-WellmanK

Similarly, ferroptosis-induced lipid peroxidation activates the NLRP3 inflammasome, triggering pyroptosis and amplifying renal inflammation

Antioxidant Protection: Helps defend against environmental aggressors and pollutants