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In a rat model of glaucoma, glutamine synthetase and the heat shock protein Hsp72 were identified as targets of oxidative stress by the formation of particular protein carbonyls [5]

Giustarini, D., Dalle-Donne, I., Lorenzini, S., Milzani, A

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However, it is also highly conserved in all eukaryotes (including human cells), leading to stagnation in the development of specific inhibitors

Introduction Cagrilintide is a long-acting, acylated analog of human amylin developed by Novo Nordisk and investigated as an amylin- and calcitonin-receptor agonist