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The authors (112) validated the conservation of organotropism across species by injecting zebrafish with mouse-derived 4T1Br4 (brain-homing) and 4T1BM2 (bone marrow-tropic) cells, and observed metastatic targeting patterns that aligned with murine experimental data

It is therefore desirable to selectively target drugs to the brain via endogenous BBB transport systems

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found that EXOs separated with commercially available kits had lower purity than those obtained by centrifugation techniques (Van Deun et al., 2014)

Taking into consideration that the cystine/glutamate exchanger is present in the astrocytic end feet [29], this exchanger is mainly involved in the maintenance of extra-synaptic Glu levels

IFITM proteins restrict viral membrane hemifusion