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It should be emphasized that exceeding the cutoff weight loss of 15 Percentage is of great clinical importance

For example, Liu and collaborators observed similar effects to those described in HCC, but in pancreatic cancer cells (Liu et al., 2018 [19])

Quinoline ring derivatives protect against aminoglycoside-induced hair cell death in the zebrafish lateral line

This approval represents the first FDA-approved drug specifically targeting mitochondrial function, establishing regulatory precedent for the mitochondrial dysfunction pathway in aging and neurodegeneration

Acknowledgements We acknowledge co-funding from the Fondazione per la Ricerca Biomedica Saverio e Isabella Cianciola and from Next Generation EU, in the context of the National Recovery and Resilience Plan, Investment PE8 Project Age-It: Ageing Well in an Ageing Society

PubMed Mihovilovic, K., Sever, M., Zoricic, I., et al