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But it lacks the ability to specifically target cancer cells and causes many side effects such as intestinal disorders, diarrhea, and skin rashes

Glucose deprivation had no significant effect on PDAC cell viability or apoptosis in the presence of TRAIL, whereas Gln deprivation markedly decreased cell proliferation and significantly activated apoptosis upon TRAIL treatment

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Therefore, to bridge the gap between mechanistic studies and clinical application, stratified randomized controlled trials that employ rigorously characterized microbial strains, standardized dosing protocols, and prespecified, patient-centered primary endpoints must be prioritized in future research

The results of an aggregate meta-analysis on PRP injections showed the staggering lack of solid scientific study about this treatment method