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The imbalance between mitochondrial fission and fusion leads to abnormal morphology of the mitochondria in spastic paraparesis [244]

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These limitations in the implementation and effectiveness of behavioral interventions emphasize the need for directed pharmacological treatment options

2-Methoxyestradiol inhibits experimental autoimmune encephalomyelitis through suppression of immune cell activation

Although the relationship has not been studied specifically in cirrhosis, sarcopenia is highly prevalent in this population and contributes to disability and poor quality of life

Fasudil can also cause vasodilation and hence was evaluated for the treatment of systemic sclerosis patients with Raynaud's phenomenon