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Ding Xue, Tsinghua University, Beijing, China)

Excessive ROS production is a major pathological mechanism of neurodegenerative diseases, and IF protects neurons by activating the Nrf2 signaling pathway, increasing the expression of antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), and reducing ROS accumulation (27)

Some laboratories prefer -80 C storage for highly hydrolytically sensitive sequences or when the peptide will be kept for more than a year

The leakage of MSCs at the implanted site also hinders its application

Blanco JC, Khatri A, Kifayat A, Cho R, Aronow WS

10.1172/JCI20039 J Clin Investig